Preface The book entitled "Synthesis and pharmacological evaluation of novel isatin derivatives" has been compiled to meet the essential requirement of the researcher for the development novel potent antiepileptic drugs. The subject matter of this work comprehensive and simple. I have tried to present this work in stepwise directions which help the researcher to develop of novel antiepileptic drug and also help them to I hope this book may be provided the better guide line to the researchers who are designing drugs for the treatment of epilepsy. The requirement of the researcher has been a major factor, kept in mind during the compiling of this book. I am sure that the work will serve the purpose of leading the researcher to the development of antiepileptic drug. I am greatly obliged to my parents. I acknowledge the encouragement, co-operation and help of my friends. They have encouraged me to write this book. I am also indebted to my family member Reeta, because she has motivated me for the research work. I convey my sincere thanks to my father Shree Rishipal for working day and night with me to complete the project for taking all pains and interest in the publication