Trends in Drug Discovery in Diabetes and Obesity

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Beschreibung

<p><b>Drug discovery strategies for next-generation anti-diabetic and anti-obesity therapies</b></p><p>Diabetes ranks as the seventh leading cause of death globally, claiming 1.5 million victims annually, yet the complexity of energy metabolism makes pharmaceutical intervention difficult-often requiring simultaneous modulation of multiple drug targets. <i>Trends in Drug Discovery in Diabetes and Obesity</i> assembles drug developers from pharma companies who share hard-to-find insight on strategies for developing more efficient therapies.</p><p>The book surveys critical drug classes including GLP-1 receptor agonists, GIP antagonists, poly-agonist drugs, and long-acting insulin variants, covering both peptide and small molecule approaches. Selected case studies detail the discovery pathways of recently approved drugs, providing direct insight into the decision-making and optimization processes that led from target identification through clinical validation to market approval.</p><p>Readers will also find:</p><ul><li>Reviews of recent therapy developments and emerging treatment paradigms reshaping the current diabetes and obesity pharmacological landscape</li><li>Evaluation of poly-agonist drug potential and their projected role in future multi-target therapeutic strategies for metabolic disorders</li><li>Perspectives from industry professionals across pharmaceutical companies offering practical context rarely available in academic literature alone</li><li>Coverage of peptide drug design strategies alongside small molecule approaches for addressing complex metabolic pathway modulation challenges</li><li>Case studies tracing recently approved drugs from early discovery through optimization, illustrating real-world drug development decision frameworks</li></ul> <p>Designed for medicinal chemists, pharmaceutical chemists, and endocrinologists working in drug discovery and development, this volume delivers the strategic and mechanistic insight needed to advance the next g

Artikeldetails

EAN

9783527353309

Sprache

Englisch

Einband / Art

Buch

Maße

244 x 170 x 15 mm

Erscheinungsjahr

2026

Verlag / Hersteller

Wiley-VCH GmbH